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Dystrophic calcification (DC) is the calcification occurring in degenerated or necrotic tissue, as in hyalinized scars, degenerated foci in leiomyomas, and caseous nodules. This occurs as a reaction to tissue damage,〔(【引用サイトリンク】title=Cell Injury )〕 including as a consequence of medical device implantation. Dystrophic calcification can occur even if the amount of calcium in the blood is not elevated. (A systemic mineral imbalance would elevate calcium levels in the blood and all tissues and cause metastatic calcification.) Basophilic calcium salt deposits aggregate, first in the mitochondria, and progressively throughout the cell. These calcifications are an indication of previous microscopic cell injury. It occurs in areas of cell necrosis in which activated phosphatases bind calcium ions to phospholipids in the membrane. Calcification can occur in dead or degenerated tissue. == Calcification in dead tissue== #Caseous necrosis in T.B. is most common site of dystrophic calcification. #Liquefactive necrosis in chronic abscesses may get calcified. #Fat necrosis following acute pancreatitis or traumatic fat necrosis in breasts results in deposition of calcium soaps. #Infarcts may undergo D.C. #Thrombi, especially in veins, may produce phlebolithis. #Haematomas in the vicinity of bones may undergo D.C. #Dead parasites like schistosoma eggs may calcify. #Congenital toxoplasmosis or rubella may be seen on X-ray as calcifications in the brain. 抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』 ■ウィキペディアで「Dystrophic calcification」の詳細全文を読む スポンサード リンク
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